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Aerial view of UCSD campus looking South

Geisel Library - Nobel Laureates at UCSD

Discovery of new atmospheric reaction garners prize

Urey Hall Addition

Pacific Hall

Natural Sciences Building

The crystal structure of a group II intron in the pre-catalytic state

Geisel Library Walk

York Hall

Structure of an inhibitor of hepatitis C virus protein synthesis bound to its target in the viral ribonucleic acid (RNA) genome

ANCA probe staining amyloid plaques derived from Alzheimer’s-related Aβ peptides fluoresces as green and as yellow when derived from prion proteins (PrPSC)

Price Center

Generation of bio-resistive surface coatings on amyloids inhibits harmful protein-amyloid interactions associated with Alzheimer disease

Proposed schematic models of the interfacial binding surface of four different members of the Phospholipase A2 superfamily

Urey Hall and Pacific Hall

Characterization of the "inhibitor binding pocket" in the catalytic domain of the calcium-independent phospholipase A2 with residues within a 5 A raidus of the inhibitor shown

A Crystalline Singlet Phosphinonitrene: a Nitrogen Atom Transfer Agent

Mayer Hall

Drug candidate in orange envelope bound to UPPS

Possible binding modes for phospholipase A2 via its membrane interaction site, another allosteric site, and its catalytic site



News

Professor Neal Devaraj receives ACS Award in Pure Chemistry and National Fresenius Award
Professor Dr. Neal Devaraj receives the 2017 ACS Award in Pure Chemistry and the 2016 National Fresenius Award. The 2017 ACS Award in Pure Chemistry award is presented annually to recognize and encourage fundamental research in pure chemistry carried out in North America by young men and women. The recipient must have fewer than ten years of experience since his/her terminal degree and must have accomplished research of unusual merit for an individual on the threshold of her or his career. The 2016 National Fresenius Award is presented annually to an outstanding young scientist who has attained national recognition in the areas of research, teaching and/or administration. The award recipient must be under 35 years of age at the date of the nomination. Both of these awards will be presented at the Society’s 253rd ACS National Meeting in San Francisco, CA on Tuesday, April 4, 2017. For a complete listing of all ACS 2017 National Award winners click here

Distinguished Professor Vicki Grassian Named Associate Dean in the Division of Physical Sciences
Prof. Vicki Grassian has accepted the position of Associate Dean in the Division of Physical Sciences. Her extensive research, teaching, and administrative experience make her an exceptional addition to the Dean’s office academic leadership. Professor Grassian will begin her tenure as Associate Dean effective immediately, and will help transition the Divisional leadership to Dean Boggs when he arrives in January. She will serve as an integral part of Divisional administration, and will lead various new initiatives that will be developed over the course of the next year.

Professor Thiemens Wins Meteoritical Society's 2017 Leonard Medal
The Meteoritical Society announced the selection of Mark Thiemens, distinguished professor of chemistry and biochemistry and former dean of the Division of Physical Sciences at UC San Diego, as the recipient of the 2017 Leonard Medal. The announcement was made at the Meteoritical Society's recently-concluded annual meeting held in Berlin. The Leonard Medal is one of the highest international awards for discoveries in the origin of the solar system and planets. Thiemens' selection was in recognition of his isotopic studies using new quantum mechanically based isotope effects to investigate the origin of the solar system. The work includes studies of solar evolution, Mars origin and its atmosphere, and the Moon. His work also involved a new technique to quantify the origin and evolution of life and oxygen in the earliest history of earth as well as the ancient atmosphere of Mars. Thiemens is the fourth faculty member in the Department of Chemistry and Biochemistry at UC San Diego to win the prestigious Leonard Medal. The previous recipients were founders Harold Urey, Hans Suess, and James Arnold. The Department is unique in that all other winners are from Astrophysical, Geophysical or Earth and Planetary Sciences Departments.

CAICE Upward Bound Outreach Day, held on July 27th at the UCSD Natural Sciences Auditorium
Fifty-nine UCSD Upward Bound (a federal TRIO program) high school students attended this event. The students were diverse and ranged 9th-12th graders. They are from the San Diego and Imperial County areas. Seven CAICE undergraduate summer interns assisted at this event, as well as 9 UCSD “4C” community college summer interns who attend or just graduated from local community colleges.

Welcome new Assistant Professor Dr. Roshanak Irannejad
Dr. Roshanak Irannejad joins our biochemistry division in the winter of 2017. She is currently a Postdoc at UC San Francisco. Dr. Irannejad earned her PhD. from Thomas Jefferson University in 2010.

Professor Nathan Gianneschi named the Teddy Traylor Faculty Scholar in Organic Chemistry
Professor Dr. Nathan Gianneschi has been named the Teddy Traylor Faculty Scholar in Organic Chemistry for 2016-2021. Scholar Awards in each of the department’s four divisions were inaugurated in 2006. Each award is to be held for a 5-year term, not immediately renewable. Faculty members who do not currently hold an endowed chair or the title of Distinguished Professor (Professor, Above Scale) are eligible to be awarded a named scholarship.

Professor Rommie Amaro named the Kurt Shuler Faculty Scholar in Physical Chemistry
Professor Dr. Rommie Amaro has been named the Kurt Shuler Faculty Scholar in Physical Chemistry for 2016-2021. Scholar Awards in each of the department’s four divisions were inaugurated in 2006. Each award is to be held for a 5-year term, not immediately renewable. Faculty members who do not currently hold an endowed chair or the title of Distinguished Professor (Professor, Above Scale) are eligible to be awarded a named scholarship.

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Message from the Chair

Partho Ghosh, Chair



Faculty Spotlight

View profile for Albizati, Kim
Albizati, Kim

Chemical Education

View profile for Amaro, Rommie
Amaro, Rommie

Computational Chemistry and Biophysics

View profile for Baker, Timothy
Baker, Timothy

Macromolecular, cryoelectron microscopy and three-dimensional, image-reconstruction techniques.

View profile for Brydges, Stacey
Brydges, Stacey

Chemical Education: Development of context-rich curriculum; Use of collaborative learning strategies in large lectures; Communication of chemistry

View profile for Burkart, Michael
Burkart, Michael

Natural product synthesis/biosynthesis, Biological chemistry and enzymology, Metabolic engineering.

View profile for Bussey, Thomas
Bussey, Thomas

Chemical Education: Visual Literacy in Science, Biochemistry Education, Nano Science Education, K-20 Professional Development, and STEM Career Development

View profile for Cohen, Seth
Cohen, Seth

Bioinorganic and coordination chemistry. Metalloprotein inhibitors and supramolecular materials.

View profile for Continetti, Robert
Continetti, Robert

Dissociation dynamics of transient species, three-body reaction dynamics, novel mass-spectrometric methods

View profile for Crowell, John
Crowell, John

Materials chemistry, surface kinetics of metals/semiconductors, CVD, photo-induced deposition, thin-film spectroscopy.

View profile for Dennis, Edward
Dennis, Edward

Biochemistry: phospholipase A2, signal transduction in macrophages, lipid maps, prostaglandin regulation, mass spec of lipids and proteins.

View profile for Devaraj, Neal
Devaraj, Neal

Biomimetic Chemistry, Molecular Imaging, Chemical Biology

View profile for Dixon, Jack
Dixon, Jack

Protein Tyrosine Phosphatase, Dual=specific Phosphatase, PTEN

View profile for Donoghue, Daniel
Donoghue, Daniel

Fibroblast Growth Factor Receptors (FGFRs) in Human Cancer

View profile for Figueroa, Joshua
Figueroa, Joshua

Inorganic and Organometallic Chemistry: Synthesis, Small Molecule Activation and New Transformations.

View profile for Galperin, Michael
Galperin, Michael

Electron Transport in Condensed Phases. Dissipation and Relaxation Processes. Non-equilibrium Open Quantum Systems. Molecular Electronics.

View profile for Ghosh, Gourisankar
Ghosh, Gourisankar

Biochemistry and biophysics: transcription, signaling, pre-mRNA splicing, mRNA transport, protein-protein, protein-DNA and protein-RNA interactions

View profile for Ghosh, Partho
Ghosh, Partho

Mechanisms of bacterial and protozoan pathogenesis, and host response against infectious microbes.

View profile for Gianneschi, Nathan
Gianneschi, Nathan

Bioorganic chemistry, Supramolecular Chemistry, Bionanotechnology, Materials, Synthesis

View profile for Godula, Kamil
Godula, Kamil

Nanotechnologies for analysis of glycan function during development. Glycomaterials for stem cell-based tissue regeneration.

View profile for Grassian, Vicki
Grassian, Vicki

Surface science of complex environmental interfaces: heterogeneous atmospheric chemistry of sea spray and mineral dust; aerosol impacts on climate; applications and implications of nanoscience and nanotechnology in environmental processes and health.

View profile for Hermann, Thomas
Hermann, Thomas

RNA as a Drug Target.

View profile for Jennings, Patricia
Jennings, Patricia

Biophysical chemistry: protein structure, dynamics and folding; 2, 3 and 4D NMR spectroscopy; PCR; equilibrium and kinetic-fluorescence, absorbance and circular dichroism spectroscopies

View profile for Joseph, Simpson
Joseph, Simpson

Molecular Mechanism of Protein Synthesis

View profile for Kim, Judy
Kim, Judy

Biophysical chemistry: Spectroscopic studies of membrane protein folding and dynamics

View profile for Komives, Elizabeth
Komives, Elizabeth

Structure, function, dynamics and thermodynamics of protein-protein interactions: NMR, mass spectrometry and kinetics

View profile for Kubiak, Clifford
Kubiak, Clifford

Inorganic, materials, and physical chemistry: electron transfer, catalysis, fixation and utilization of carbon dioxide.

View profile for Kummel, Andrew
Kummel, Andrew

STM/STS of gate oxides on compound semiconductors and adsorbates on organic semiconductor

View profile for Lindenberg, Katja
Lindenberg, Katja

Theoretical chemical physics: non-equilibrium statistical mechanics; stochastic processes; nonlinear phenomena; complex systems; condensed matter.

View profile for McCammon, James
McCammon, James

Statistical mechanics and computational chemistry, with applications to biological systems

View profile for Molina, Mario
Molina, Mario

Physical Chemistry: Gas Phase Chemical Kinetics and Photochemistry; Chemistry of Atmospheric Aerosols; Air Pollution in Megacities of the Developing World

View profile for Molinski, Tadeusz
Molinski, Tadeusz

Organic chemistry of marine natural products, synthesis, NMR, and biomedical applications

View profile for Muller, Ulrich
Muller, Ulrich

Evolution of catalytic RNAs, and the Origin of Life

View profile for O'Connor, Joseph
O'Connor, Joseph

Organotransition metal; organic; physical organic; bioorganometallic; synthetic; and inorganic chemistry

View profile for Opella, Stanley
Opella, Stanley

NMR structural studies of proteins in membranes and other supramolecular assemblies

View profile for Paesani, Francesco
Paesani, Francesco

Theoretical chemical physics of complex interfaces of relevance to the environment

View profile for Perrin, Charles
Perrin, Charles

Physical-organic chemistry: stereoelectronic effects; hydrogen bonding; isotope effects; ionic solvation; naked anions; malonic anhydrides

View profile for Pomeroy, Robert
Pomeroy, Robert

The application of analytical chemistry to forensic, environmental and industrial chemistry, then bridge these experiences into the classroom. This also includes the role technology and instrumentation play in discovery and problem solving.

View profile for Prather, Kimberly
Prather, Kimberly

Environmental, physical/analytical chemistry: gas/particle processes of tropospheric significance; mass spectrometry; laser-based analysis techniques.

View profile for Rheingold, Arnold
Rheingold, Arnold

Inorganic chemistry: Small-molecule crystallography, synthesis of transition metal/p-block clusters

View profile for Rinehart, Jeffrey
Rinehart, Jeffrey

Inorganic, materials, and magnetochemistry

View profile for Sailor, Michael
Sailor, Michael

Nanomaterials: porous silicon, chemical and biological sensors, biomaterials, electrochemistry

View profile for Sawrey, Barbara
Sawrey, Barbara

Chemical education: development of computer-based multimedia to assist student learning of complex scientific processes and concepts

View profile for Schimpf, Alina
Schimpf, Alina

Spectroscopy, Inorganic Chemistry, Nanoscale Materials

View profile for Schmidt, Valerie
Schmidt, Valerie

Organic Synthesis, Catalysis, Organometallic Synthesis, Methodology Development

View profile for Sinha, Amitabha
Sinha, Amitabha

Experimental physical chemistry: photochemistry; laser spectroscopy; reaction dynamics of vibrationally excited molecules

View profile for Tauber, Michael
Tauber, Michael

Physical chemistry; Optical and magnetic spectroscopy; Fundamental studies of charge transport and solvation; Applications to energy conversion and energy storage.

View profile for Taylor, Susan
Taylor, Susan

Structure, Function, Dynamics, and Localization of PKA as a Prototype for the Protein Kinase Superfamily.

View profile for Tezcan, Faik
Tezcan, Faik

Bioinorganic and biophysical chemistry; Metalloprotein structure, function and biosynthesis; Biomaterials

View profile for Theodorakis, Emmanuel
Theodorakis, Emmanuel

Synthetic, Medicinal, Bioorganic and Biological Chemistry, Methods and Strategies in Natural Products Chemistry

View profile for Thiemens, Mark
Thiemens, Mark

Atmospheric chemistry: physical chemistry of isotope effects; solar system formation

View profile for Toor, Navtej
Toor, Navtej

Structure and Function of Introns and Retroelements

View profile for Tor, Yitzhak
Tor, Yitzhak

Ligand-nucleic acid interactions; Antiviral and antibacterial agents; Fluorescent nucleosides and nucleotides; Cellular delivery vehicles

View profile for Trogler, William
Trogler, William

Inorganic chemistry: polymer chemistry; nanomaterials.

View profile for Tsien, Roger
Tsien, Roger

Chemical biology; design, synthesis, and application of molecular probes of biological function

View profile for Villa, Elizabeth
Villa, Elizabeth

Structural Cell Biology, Cryo-Electron Microscopy, Multiscale modeling

View profile for Wang, Wei
Wang, Wei

epigenomics, cellular reprogramming, protein recognition, computational biology, systems biology

View profile for Weare, John
Weare, John

Physical chemistry: calculations of the dynamics of complex systems; theoretical geochemistry

View profile for Weizman, Haim
Weizman, Haim

Chemical education, Bioorganic chemistry

View profile for Xiong, Wei
Xiong, Wei

Investigation of charge transfer mechanism in nanomaterials with novel ultrafast spectroscopies

View profile for Yang, Jerry
Yang, Jerry

Bioorganic Chemistry, Molecular Self-Assembly, Molecular Synthesis, Materials Chemistry, Bionanotechnology

View profile for Yuen Zhou, Joel
Yuen Zhou, Joel

Molecular photonics: theory

View profile for Zid, Brian
Zid, Brian

Gene Expression Control During Stress; mRNA Localization to Membrane-Less Compartments


Events and Seminars

08/31/2016 (Wed) at 02:00 PM
MS Thesis Defense
Ivan Andrew Kozachenko
Studies of Membrane Protein Folding by Bimolecular Fluorescence Quenching
09/01/2016 (Thu) at 01:30 PM
Thesis Defense
Benjamin D Saylor
Identification and Modification of Fatty Acid Modifying Enzyme From Staphylococcus aureus
09/07/2016 (Wed) at 12:00 PM
Thesis Defense
Kirk Alan Reynolds
Discovery and characterization of calcium-dependent antibiotics viaactivation of a silent natural product gene cluster
09/29/2016 (Thu) at 12:00 PM
Biochemistry Seminar
Professor James Fraser
Birth of the Cool: Multitemperature Multiconformer X-Ray Crystallography Predicts the Response of Allosteric Perturbations
10/03/2016 (Mon) at 11:00 AM
Organic Seminar
Professor Nathaniel S. Finney
TBA
10/06/2016 (Thu) at 12:00 PM
Biochemistry Seminar
Professor Francesca Massi
TBA
10/10/2016 (Mon) at 11:00 AM
Organic Seminar
Professor William C. K. Pomerantz
TBA
More....